Sanches is a Portuguese surname. The Spanish version of this name is Sánchez. Notable people with the surname include:
Afonso Sanches (1289–1329), Portuguese nobleman
António Nunes Ribeiro Sanches (1699–1783), Portuguese physician and philosopher
Brian Sanches (born 1978), American baseball player
Francisco Sanches (c.1550–1623), Portuguese-Galician philosopher
Manuel Estêvão Sanches (born 1979), Portuguese-Cape Verdean footballer
Renato Sanches (born 1997), Portuguese footballer
Simon Sanches, Dutch navy nurse and laboratory technician who planned to commit a coup d'état in Suriname
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