Mylene or Mylène is a given name, a contraction of Marie-Hélène. Notable people and characters with the name include:
Mylène Demongeot (1935–2022), French actress
Mylene Dizon (born 1976), Filipino actress and model
Mylène Farmer, French singer-songwriter
Mylène Jampanoï (born 1980), French actress
Mylene Flare Jenius, fictional character in the Macross universe
Mylène Lamoureux, Canadian ice-dancer
Mylene Ong (born 1991), Singaporean Olympic swimmer
Mylene Paat (born 1994), Filipino volleyball player
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